The Journal of physiologyAnimalsrac1 GTP-Binding ProteinGlucoseMuscle FibersSkeletal
Breast cancer cell-conditioned media inhibit growth and reduce basal and insulin-stimulated glucose uptake by inhibiting Rac1 activation in rat myotubes.
Mona Sadek Ali, Stine Bitsch-Olsen, Emma Frank, Scott Sebastian Birch Themsen, Edmund Battey, Mirela Perla, Steffen Henning Raun, Steven de Jong, Lykke Sylow
Published: 202510.1113/JP288099
Abstract
Metabolic disorders are common in women with breast cancer, raising mortality and recurrence rates, but their causes remain poorly understood. Given the importance of skeletal muscle metabolism in glucose homeostasis, we investigated the effect of br…
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