Experimental physiology
Sex-dependent effects of a high-fat diet-induced obesity model on cerebrovascular health and brain metabolism.
Nicole N Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S Prabhu, Kate Karelina, Eric E Kelley, Randy W Bryner, Dharendra Thapa, Paul D Chantler
Published: 202510.1113/EP093187
Abstract
Mid-life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post-translational modification that regulates several mitochondri…
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