Experimental physiology
Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses.
Jessica F Briffa, Sogand Gravina, Viktoria F Richter, Dayana Mahizir, Kristina Anevska, Yeukai T M Mangwiro, James S M Cuffe, Fadi Charchar, Glenn D Wadley, Deanne H Hryciw, Karen M Moritz, Mary E Wlodek
Published: 202510.1113/EP092622
Abstract
Uteroplacental insufficiency impairs kidney development and programs male-onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting tha…
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