Transfusion
Generation of enzyme-converted type O whole blood from type A whole blood: A translational study using swine whole blood.
Craig D Nowadly, Brian G Casleton, Manuel Y Caballero, Hui Xia, David S Ediger, Haisle Moon, Isis Ip, Spencer S Macdonald, Karolina Jones, Peter Rahfeld, Jayachandran N Kizhakkedathu, Stephen G Withers, Jason M Rall
Published: 202510.1111/trf.70049
Abstract
BACKGROUND: Low-titer O whole blood (LTOWB) is increasingly used to improve trauma outcomes, but maintaining supplies remains challenging, particularly in austere environments. This study evaluated EnzAO1 (FpGalNAcDeAc) and EnzAO2 (FpGalNase) to gene…
Preview only. Read the full abstract at the source