Pathology internationalHumansLymphomaLarge B-CellDiffuseCyclin-Dependent Kinase Inhibitor p16
Significance and Utility of Immunohistochemical MTAP Expression to Predict CDKN2A Genomic Status in Diffuse Large B-Cell Lymphoma.
Kozue Ito, Hiroki Imada, Marino Nagata, Takahisa Yamashita, Keisuke Sawada, Takumi Takahashi, Wataru Yamamoto, Natsuko Takayanagi, Takayuki Tabayashi, Jun-Ichi Tamaru, Morihiro Higashi, Shuji Momose
Published: 202610.1111/pin.70072
Abstract
Recent genomic studies have delineated genetic subtypes of diffuse large B-cell lymphoma (DLBCL), and CDKN2A deletion has been reported as an adverse prognostic factor across several of these subtypes. Because MTAP, located adjacent to CDKN2A on 9p21…
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