Annals of the New York Academy of Sciences
Proteome-Wide Mendelian Randomization Implicates Shared Necroptosis-Ferroptosis Effectors in Causal Pathways of Multiple Sclerosis Susceptibility.
Wu Yan, Wang Jianhong, Jiang Wen, Zhang Linming
Published: 202510.1111/nyas.70162
Abstract
Multiple sclerosis (MS) is a chronic neurodegenerative disorder for which dysregulated ferroptosis and necroptosis have demonstrated pathological associations but these lack causal validation in disease susceptibility. This study employed proteome-wi…
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