Annals of the New York Academy of SciencesHumansProto-Oncogene Proteins c-aktMelanomaSkin NeoplasmsPhosphatidylinositol 3-Kinases
COMMD4 Drives Skin Cutaneous Melanoma Progression by Targeting PI3K-p85 to Activate PI3K-AKT.
Xiaoqiang Liu, Luojia Liu, Qiaoling Wang, Lufan Xia, Fangqing Zuo, Jinrui Yang, Kaibang Zheng, Yunfan Tang, Jingjing Guo, Xiaoping Yu, Boye Qi, Hanghang Zhou, Ying Chen, Jiaping Zhang, Xuanfen Zhang
Published: 202610.1111/nyas.70141
Abstract
Skin cutaneous melanoma (SKCM), the most aggressive form of cutaneous malignancy globally, remains poorly understood in terms of its molecular drivers. Although the copper metabolism MURR1 domain (COMMD) protein family has been associated with oncoge…
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