Liver international : official journal of the International Association for the Study of the LiverHumansEpithelial CellsInsulin-Like Growth Factor Binding Protein 4MacrophagesLiver Cirrhosis
IGFBP4 is a Metric for Primary Biliary Cholangitis and Attenuates Biliary Epithelial Cell Injury.
Xing Zhou, Shuyu Shao, Danning Yang, Ziyan Cheng, Toshihiro Tanaka, Patrick S C Leung, Koichi Tsuneyama, Aftab A Ansari, William M Ridgway, Pietro Invernizzi, Christopher L Bowlus, M Eric Gershwin, Weici Zhang
Published: 202610.1111/liv.70525
Abstract
BACKGROUND AND AIMS: Immune-mediated bile duct injury is the primary histological feature of autoimmune cholestatic liver diseases. Macrophages, the most abundant immune cell population in the liver, have been postulated to play a critical role in bi…
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