The journal of obstetrics and gynaecology researchHumansValproic AcidPregnancyFemaleAnticonvulsants
Safety of Valproic Acid Use in Pregnant Women: A Systematic Review and Meta-Analysis.
Xinying Yang, Yiqi Sun, Zixin Hua, Taoran Li, Xingang Li, Pengqiang Du
Published: 202510.1111/jog.70121
Abstract
OBJECTIVE: To evaluate valproic acid (VPA) safety in pregnancy versus other antiepileptic drugs (AEDs), focusing on fetal malformation risks. METHODS: A literature search was conducted across PUBMED, MEDLINE, EMBASE, and Web of Science databases. Two…
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