Journal of the peripheral nervous system : JPNSNiacinamideNerve RegenerationPyridinium CompoundsHumansMale
Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration.
Simone Thomas, Remi Ben-Davies, Aysel Cetinkaya-Fisgin, Xindan Hu, Xiaoling Li, Sarah Stewart, Baohan Pan, Jeffery L Twiss, Rajiv R Ratan, Dianna Willis, Michael Polydefkis, Ahmet Höke
Published: 202610.1111/jns.70101
Abstract
BACKGROUND AND AIMS: Recent preclinical studies have shown that nicotinamide adenine dinucleotide (NAD+) plays a critical role in molecular mechanisms of axon degeneration, and reductions in NAD+ levels are associated with axonal degeneration. Nicoti…
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