Journal of neurochemistryPolypyrimidine Tract-Binding ProteinHumansRetinal Pigment EpitheliumNeuronsProtein Isoforms
Isoform-Specific Splicing of ANK2 by PTBP2 Orchestrates Retinal Pigment Epithelial-to-Neuron Fate Conversion.
Yun-Xi Ma, Yan-Ke Zhang, Jun Li, Bing-Lin Zhu
Published: 202610.1111/jnc.70358
Abstract
Direct lineage reprogramming represents a promising strategy to convert somatic cells into neurons, offering regenerative potential. While transcription factor-based approaches have been extensively studied, the role of post-transcriptional regulatio…
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