Journal of neurochemistryAnimalsNeuronsEnteric Nervous SystemRatsDeoxycholic Acid
The Microbiota-Derived Metabolite Deoxycholic Acid Regulates Enteric Neuron Activity and Connectivity.
Morgane E Le Dréan, Baptiste Ganachaud, Maëva Rebion, Justine Marchix, Catherine Le Berre-Scoul, Philippe Hulin, Magalie Feyeux, Sophie Talon, Michel Neunlist, Martial Caillaud, Hélène Boudin
Published: 202610.1111/jnc.70351
Abstract
Secondary bile acids (BAs) are metabolites produced by the gut microbiota and shown to impact digestive functions, at least in part through the enteric nervous system (ENS). In the ENS, enteric neurons express the BA receptor Takeda G protein-coupled…
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