Genes to cells : devoted to molecular & cellular mechanismsReactive Oxygen SpeciesCellular SenescenceDNA DamageHumansrac1 GTP-Binding Protein
Epsin 3 Promotes Cellular Senescence Through Reactive Oxygen Species-Mediated Induction of DNA Damage.
Yukihiro Ikegaki, Anju Terachi, Shunsuke Yamao, Taiki Nagano, Tetsushi Iwasaki, Shinji Kamada
Published: 202510.1111/gtc.70067
Abstract
Cellular senescence is caused by various stresses, including DNA damage, oxidative stress, oncogene activation, and telomere shortening. However, the detailed molecular mechanisms of cellular senescence have yet to be elucidated. Recently, using comp…
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