The FEBS journal
PEMT-mediated phospholipid imbalance promotes age-associated metabolic dysfunction-associated steatotic liver disease progression.
Xilong Gao, Jiahui Gong, Yichao Hou, Li Lin, Yanling Hao, Zhengyuan Zhai, Ming Zhang, Hao Zhang, Juan Chen, Fa-Zheng Ren, Bing Fang, Liang Zhao
Published: 202510.1111/febs.70349
Abstract
Metabolic dysfunction-associated steatotic liver disease [MASLD; previously known as nonalcoholic fatty liver disease (NAFLD)] is a prevalent chronic liver disorder strongly associated with aging, yet the mechanisms underlying age-related hepatic lip…
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