The FEBS journal
Loss of arginase 2 disrupts striatum-specific polyamine homeostasis.
Martyna Nalepa, Omar Basheer, Mariusz Radkiewicz, Katarzyna Skowrońska, Aleksandra Skweres, Aleksandra Owczarek, Agata Dalka, Wojciech Hilgier, Magdalena Zielińska, Emilia Samborowska, Michał Węgrzynowicz
Published: 202510.1111/febs.70313
Abstract
Arginase converts arginine (Arg) to ornithine (Orn), regulating their availability for the metabolic pathways that utilize these amino acids. The roles of arginase isoenzymes, ARG1 and ARG2, vary by cell type, tissue, and physiological state. In the…
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