The FEBS journal
Cryo-EM structure of pentameric C-reactive protein in complex with monoclonal IgG antibodies.
Andrey V Moiseenko, Alexander V Kalikin, Philipp S Orekhov, Nadezhda A Byzova, Anatoly V Zherdev, Konstantin V Shaitan, Boris B Dzantiev, Olga S Sokolova
Published: 202510.1111/febs.70310
Abstract
C-reactive protein (CRP) plays a central role in innate immunity and serves as a key biomarker of inflammation. Despite its clinical importance, the structural basis of CRP interactions with antibodies remains poorly characterized. Using cryo-electro…
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