Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products.

1,8-cineole synthase from Streptomyces clavuligerus (bCinS) is the only known bacterial terpene synthase that shows exclusive activity towards the monoterpene substrate geranyl diphosphate (GPP; C10). Unlike most plant terpene synthases, bCinS is a h…

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