Epilepsia
Optimizing responsive neurostimulation targeting based on interictal high-frequency oscillations and phase-amplitude coupling.
Sotaro Kanai, Atsuro Daida, Yipeng Zhang, Yuanyi Ding, Tonmoy Monsoor, Joe X Qiao, Noriko Salamon, Eric Ronne, Samuel S Ahn, Shaun A Hussain, Raman Sankar, Aria Fallah, William Speier, Vwani Roychowdhury, Jerome Engel
Published: 202510.1111/epi.18675
Abstract
OBJECTIVE: This study was undertaken to determine whether interictal high-frequency oscillations (HFOs) and phase-amplitude coupling (PAC) can serve as spatial biomarkers on intracranial electroencephalography (iEEG) to guide responsive neurostimulat…
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