Epilepsia
Nanoparticle-encapsulated neuropeptide Y provides robust seizure protection in SCN1A-derived epilepsy.
Samantha L Reed, Lauren M Aiani, Eesha Faiz, Emmanuel Adediran, Morris Benveniste, Kevin S Murnane, Martin D'Souza, Andrew Escayg, Jennifer C Wong
Published: 202510.1111/epi.18649
Abstract
OBJECTIVE: Neuropeptides have garnered great interest as potential treatments for epilepsy due to their impact on neuronal excitability through modulation of ion channels and neurotransmitter receptor activity. Neuropeptide Y (NPY) is a 36-amino acid…
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