European journal of oral sciencesAnimalsPeriodontitisMiceReceptorAnaphylatoxin C5a
Complement C5a receptor antagonist in the treatment of experimental periodontitis in mice.
Yan Chen, Zhuangying Chen, Yan Li, Junlong Hu, Yue Zhang, Zhongqiang Han, Mingyue Liu
Published: 202610.1111/eos.70054
Abstract
Periodontitis arises from dysbiosis of the oral microbiome and excessive host immune responses, with the C5a-C5aR axis playing a key role in destructive inflammation. This study evaluated the efficacy of the C5aR antagonist W54011 in treating experim…
Preview only. Read the full abstract at the source