European journal of haematology
Microbiome-Based Modeling of CAR-T Therapy Response in Lymphoma: Insights From Shotgun Metagenomics Sequencing.
Rafael Hernani, Eliseo Albert, Carlos Hernani-Morales, Sheila Zúñiga, Ana Benzaquén, Laura González-Castillo, Ester Colomer, Júlia Morell, José Francisco Català-Senent, José Luis Piñana, Estela Giménez, Ariadna Pérez, Juan Carlos Hernández-Boluda, Ignacio Arroyo, Marcos Rivada
Published: 202610.1111/ejh.70121
Abstract
The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell-driven cancer immunotherapies. However, clinical studies supporting microbiota-based interventions in chimeric antigen receptor T-cell…
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