European journal of haematology
Ferritin H Knockout Induces Differential Immunomodulatory Drug Responses in Multiple Myeloma Cell Lines.
Aarti Sharma, Latha Pathangey, Sinto Sebastian Chirackal, Kevin G Shim, Rafael Fonseca, Sundararaman Swaminathan
Published: 202510.1111/ejh.70084
Abstract
BACKGROUND: Immunomodulatory agents (IMiDs) are a cornerstone in the successful management of multiple myeloma (MM). However, acquired IMiD resistance leading to disease relapses remains a major barrier. Hydrogen peroxide generation and oxidative str…
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