European journal of clinical investigationHumansGiant Cell ArteritisPolymyalgia RheumaticaCellular SenescenceInterleukin-6
Cellular senescence in giant cell arteritis and polymyalgia rheumatica: From mechanisms to therapeutic opportunities.
Yiting Luo, Fan Yang, Yanlin He, Jin Lin, Weiqian Chen
Published: 202610.1111/eci.70166
Abstract
BACKGROUND: Giant cell arteritis (GCA) and (PMR) are inflammatory rheumatic disorders whose pathogenesis are unclear. The interleukin (IL)-6 receptor inhibitor is the first approved biologic agent for GCA and PMR, reducing relapse rates and cumulativ…
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