Diabetes, obesity & metabolism
Methylglyoxal-derived hydroimidazolone (MG-H1) is a novel marker of insulin resistance in Japanese individuals, disturbing insulin signalling via mTORC2 in cultured myocytes.
Sonoko Kitao, Tsuyoshi Okura, Yuichi Ito, Satomi Endo, Yoshinori Ichihara, Tatsuya Sawano, Risa Nakamura, Kazuhiko Matsuzawa, Yuri Nomi, Etsuko Ueta, Yuzuru Otsuka, Keiko Nagata, Junichiro Miake, Shin-Ichi Taniguchi, Kazuhiro Yamamoto
Published: 202610.1111/dom.70489
Abstract
BACKGROUND AND AIMS: Methylglyoxal-derived hydroimidazolone (MG-H1), one of the advanced glycation end-products (AGEs), has been a potential biomarker of type 2 diabetes (T2DM), which is strongly related to insulin resistance. However, the relationsh…
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