Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and IrelandHumansRectal NeoplasmsWatchful WaitingDecision MakingShared
A randomized phase III trial of structured tumour response surveillance and shared decision-making for organ preservation in rectal cancer - PRODIGE 101-GRECCAR 20-EVAREC trial protocol.
Barbara Noiret, Véronique Vendrely, Alexis Delattre, Adrien Vavasseur, Hélène Maillou-Martinaud, Stéphanie Nougaret, Jérémie Jacques, Thibaud Haaser, Côme Lepage, Quentin Denost
Published: 202610.1111/codi.70371
Abstract
AIM: Standard management with chemoradiotherapy (CRT) or total neoadjuvant therapy (TNT) followed by total mesorectal excision (TME) reduces local recurrence but often is associated with significant long-term functional impairment. Organ preservation…
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