Cancer science
Regulation of R-Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment.
Miho M Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo
Published: 202510.1111/cas.70272
Abstract
R-loops are three-stranded nucleic acid structures comprising an RNA/DNA hybrid and a displaced single-stranded DNA. While transient R-loop formation is essential for various physiological processes, their persistent accumulation leads to genomic ins…
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