British journal of pharmacology
Antidiabetic DPP4 inhibitor Attenuates Intervertebral Disc Degeneration via Macrophage-Nucleus Pulposus Cell Crosstalk.
Chen-Cheng Zhou, Cheng-Long Xie, Xiang-Cheng Zhang, Zhuo-Fan Zeng, Yi-Feng Shi, Yi-Tian Yu, Su-Yu Ying, Yu-Rui Wu, Zi-Han Dai, Wen-Tian Cao, Hai-Wei Ma, Gang Zheng
Published: 202610.1111/bph.70283
Abstract
BACKGROUND AND PURPOSE: Intervertebral disc degeneration (IVDD), a leading cause of low back pain, lacks effective disease-modifying therapies. Diabetes exacerbates IVDD risk, but the causal mechanisms and therapeutic potential of glucose-lowering ag…
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