British journal of pharmacology
6‴-Feruloylspinosin ameliorates pressure overload-induced heart failure with comorbid insomnia through the activation of RORα.
Yan Yan, Shuaishuai Gong, Minhui Sun, Zhekai Huang, Lan Gao, Xinxin Li, Boyang Yu, Junping Kou, Chenhui Du, Fang Li
Published: 202510.1111/bph.70255
Abstract
BACKGROUND AND PURPOSE: Targeting the retinoid-related orphan receptor α (RORα) signalling pathway represents a promising therapeutic strategy for cardiovascular diseases comorbid with insomnia. Here, we identify 6‴-feruloylspinosin (6-FS) as a poten…
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