British journal of haematologyHumansHemoglobinuriaParoxysmalMaleFemale
A single-centre, real-world study on the efficacy and recovery of inflammatory cytokine levels of C5 complement inhibitor therapy in patients with paroxysmal nocturnal haemoglobinuria.
Mengting Che, Chaomeng Wang, Yongchun Li, Liyan Li, Honglei Wang, Yingying Chen, Zhaoyun Liu, Lijuan Li, Hui Liu, Rong Fu
Published: 202510.1111/bjh.70156
Abstract
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare clonal disorder caused by PIG-A mutations and characterized by complement-mediated haemolysis. C5 inhibitors are recommended as first-line therapy for PNH with high disease activity. We retrospecti…
Preview only. Read the full abstract at the source