Basic & clinical pharmacology & toxicologyAnimalsJanus Kinase 2Oxidative StressSTAT3 Transcription FactorCerebral Hemorrhage
Bergaptol Alleviates Oxidative Stress and Inflammation in Intracerebral Haemorrhage Mice via JAK2/STAT3 and NF-κB Pathways, Improving Neurological Function.
Jianbing Wu, Zhangchao Guo, Xiaohuan He, Liyuan Yang, Jie Zhang, Lijuan Shu, Chunfu Du
Published: 202510.1111/bcpt.70135
Abstract
BACKGROUND: Bergaptol has demonstrated various pharmacological activities, including antitumor, anti-inflammatory and neuroprotective effects. However, its therapeutic potential and underlying mechanisms in intracerebral haemorrhage (ICH) remain elus…
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