Allergy
Long-Term Attenuation of Vascular Hyperpermeability in a Hereditary Angioedema Mouse Model by Adenine Base Editing.
Yang Wang, Yuxuan Kong, Yingjie Zhang, Yunjie He, Wei Wang, Yuanbin Lu, Juan Meng, Huijun Yuan
Published: 202510.1111/all.70152
Abstract
BACKGROUND: Hereditary angioedema (HAE) is a rare and potentially life-threatening disorder caused by dysregulated kallikrein-kinin signaling and bradykinin-induced vascular hyperpermeability. Current therapies targeting this pathway are effective bu…
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