Monoclonal Antibody Therapies in Alzheimer's Disease: A Guide for Emergency Physicians.
Scott Wrigley, Andrew L H Huynh, Sanka Amadoru, Henry Zeimer, Irene Tan, Michael Woodward, George Braitberg, Paul Andrew Yates
Abstract
Open AccessWhilst the advent of novel disease-modifying medications for Alzheimer's disease represents potential benefit for patients and caregivers, they may be associated with adverse events that present important considerations for emergency and primary care. This article seeks to highlight some of the challenges Emergency Departments may encounter in relation to clinical presentations of people being treated with novel anti-amyloid monoclonal antibodies in the Australian context. Given the potential for harm if not recognised and managed appropriately, it is imperative that emergency clinicians are aware of possible treatment-related adverse events and have access to appropriate decision-making support and resources.