Clinical and experimental pharmacology & physiologyGemcitabineDeoxycytidinePancreatic NeoplasmsHumansDiterpenes
Bharangin, A Diterpenoid, Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine Through Involvement of Long Non-Coding RNAs and Nuclear Factor-κB.
Nikee Awasthee, Anusmita Shekher, Ankit Srivastava, Subash Chandra Gupta
Published: 202610.1111/1440-1681.70097
Abstract
Pancreatic cancer (PaCa) manifests as an aggressive tumour due to the late occurrence of early symptoms. The overall 5-year survival rate of PaCa is merely 2%-9%. Bharangin (BG), a diterpenoid quinonemethide known for its anti-cancer activities, was…
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