Clinical and experimental pharmacology & physiologyAnimalsOxidative StressTelomeraseMiceProgeria
Mitochondrial Oxidative Stress and Cardiac Dysfunction in TERT Deficient Progeria Mice.
Zandong Zhou, Yunpeng Zhang, Rui Zhao, Daiqi Liu, Bingxin Xie, Qingling Zhang, Gary Tse, Feng Wang, Tong Liu
Published: 202510.1111/1440-1681.70082
Abstract
BACKGROUND: Heart failure (HF) is a major cause of hospitalisation in the elderly. Its incidence increases with aging and the presence of risk factors such as hypertension and diabetes. Aging-related myocardial fibrosis, characterised by alterations…
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