Genes & development
B-lineage commitment is dependent on a reversible epigenetic switch.
Johanna Tingvall-Gustafsson, Kim Hellerstedt, Jonas Ungerbäck, Mikael Sigvardsson
Published: 202510.1101/gad.353002.125
Abstract
To increase our understanding of the interplay between transcription factor networks and the epigenetic landscape in early B-lymphoid development, we conducted combined SC-RNA/ATAC-seq analyses of bone marrow progenitor populations. Based on changes…
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