Open biologyReceptor-Interacting Protein Serine-Threonine KinasesProtein KinasesNecroptosisHumansAnimals
Spotted: RIPK3 and MLKL assembling necroptotic complexes.
Verónica Martínez-Osorio, Uris Ros, Ana J García-Sáez
Published: 202610.1098/rsob.250236
Abstract
Necroptosis is a form of regulated cell death (RCD) that evolved as a defence against pathogenic infection. Unlike caspase-dependent RCD, necroptosis, in its canonical form, is driven by receptor-interacting protein kinase 1 and 3 (RIPK1 and RIPK3) s…
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