Open biologyAnimalsTranscription FactorsFemaleEvolutionMolecular
Evolution and expression of glial cells missing (GCM1 and GCM2) in monotremes suggest an ancient role in reproduction.
Isabella Wilson, Diana Demiyah Mohd Hamdan, Rachel van der Ploeg, Tahlia Perry, Frank Grützner
Published: 202510.1098/rsob.250083
Abstract
The glial cells missing (GCM) genes were first discovered in Drosophila and encode transcription factors important for gliogenesis. In placental mammals, GCM1 regulates several genes that are important for early placenta development, while its paralo…
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