Journal of the American College of Surgeons
Characterizing Biological Behavior Beyond Morphologic Features: Next Generation Sequencing Analysis of Large vs Small Pancreatic Cystic Lesions in a Large Multicenter Cohort of Patients.
Amudhan Kannan, Gilbert Z Murimwa, John C Mansour, Zachary A Whitham, Herbert J Zeh, Nisa M Kubiliun, Aatur D Singhi, Patricio M Polanco, Pancreatic Cancer Research Group of UTSW and UPMC
Published: 202510.1097/XCS.0000000000001681
Abstract
BACKGROUND: Large PCLs have a higher risk of malignant transformation compared to smaller PCLs, although the biological basis for this remains unclear. We aimed to study the high-risk mutation (HRM) patterns in large versus small PCLs using cyst flui…
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