NeuroreportAlzheimer DiseaseAutophagyMicroRNAsDocosahexaenoic AcidsToll-Like Receptor 4
Docosahexaenoic acid modulates microglial autophagy via miR-589-5p/toll-like receptor 4 axis in Alzheimer's disease.
Xiao-Hui Hu, Qi Jin, Jia-Li Xie, Chun-Ling Wu, Jian-Ping Pan
Published: 202610.1097/WNR.0000000000002236
Abstract
OBJECTIVE: To investigate the neuroprotective mechanism by which docosahexaenoic acid (DHA) promotes microglial autophagy via the miR-589-5p/toll-like receptor 4 (TLR4) axis in Alzheimer's disease. METHODS: In vitro, BV2 microglial cells were treated…
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