The journal of trauma and acute care surgery
Blunt trauma induces a proinvasive transcriptional program in isolated circulating human neutrophils.
Anaar E Siletz, Jeremy Yu, James Yu, Justin Wang, Ajay Prasad, C Isabella Bent, Monica D Wong, Catherine Beni, Kazuhide Matsushima, Kenji Inaba, Matthew J Martin, Young-Kwon Hong, Joseph Cuschieri, Kelly Street, J Perren Cobb
Published: 202610.1097/TA.0000000000004874
Abstract
BACKGROUND: Trauma induces a "genomic storm" of gene expression in circulating leukocytes. We hypothesized that the neutrophil contribution to this response after blunt trauma varies with the magnitude of physiologic insult. METHODS: Blunt trauma pat…
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