Shock (Augusta, Ga.)
Quantifying Nuance within Sepsis-Associated Immune Suppression toward Diagnostic Certainty.
Charles C Caldwell, Robert Maile, Monty B Mazer, Patrick W McGonagill, Christian B Bergmann, Robert W Gould, Mahil Rao, Miguel Hernández-Ríos, Ricardo F Ungaro, Tyler J Loftus, Philip A Efron, Kenneth E Remy, Scott C Brakenridge, Vladimir P Badovinac, Thomas S Griffith
Published: 202510.1097/SHK.0000000000002745
Abstract
SUMMARY: Impact of sepsis on human T-cell function and outcome was assessed. In sepsis survivors, IFNγ-production in response to T-cell stimulation remains intact, while sepsis non-survivors display exaggerated IFNγ responses to TCR-independent stimu…
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