Current opinion in infectious diseasesHumansAntiviral AgentsSARS-CoV-2Clinical Trials as TopicCOVID-19 Drug Treatment
Antiviral clinical trial design throughout the COVID pandemic: evolving endpoints and lessons learnt.
Beatrice Z Sim, Andre C Kalil, Cameron R Wolfe
Published: 202610.1097/QCO.0000000000001165
Abstract
PURPOSE OF REVIEW: Trial design during the novel coronavirus-19 (COVID-19) pandemic was stymied by significant uncertainty about the natural history of the virus, at-risk populations, and optimal patient care by investigators and clinicians alike. RE…
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