The American journal of surgical pathology
Characterizing Paratesticular Neoplasms in Proteus Syndrome.
Andres Matoso, Russell Vang, Deyin Xing, Jonathan K Killian, Paul S Meltzer, Kim M Keppler-Noreuil, Caroline Redick, Leslie G Biesecker, Christopher A Ours
Published: 202510.1097/PAS.0000000000002498
Abstract
Proteus syndrome is a rare mosaic overgrowth disorder caused by somatic activating variants in AKT1, most commonly the c.49G>A p.(Glu17Lys) variant. It predisposes individuals to asymmetric tissue proliferation and an elevated risk for both benign an…
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