Annals of medicine and surgery (2012)
Headway in multiple sclerosis therapy: the case for platinum analogues.
Zain Ali Nadeem, Umar Akram, Aalaa Saleh, Aimen Nadeem
Published: 202510.1097/MS9.0000000000003536
Abstract
Open AccessMultiple sclerosis is a chronic neuroinflammatory disease associated with significant morbidity. Currently available pharmacotherapeutics are associated with several adverse effects. This letter discusses the potential of carboplatin, a platinum analog, which has recently shown promising results. We delve into the mechanisms of action and review the literature for potential adverse effects of carboplatin therapy.