Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosisHumansHemophilia AT-LymphocytesRegulatoryFactor VIII
Understanding of the roles of CD4 + CD25 + T cells and Tregs in development of anti-FVIII in hemophilia A: insights for inhibitor development prevention.
Emre Akkaya, Basak S Koc, Umut C Kucuksezer, Aysenur Kokoglu, Esin Cetin Aktas, Gunnur Deniz, Sema Genc, Bulent Zulfikar
Published: 202510.1097/MBC.0000000000001393
Abstract
Hemophilia A, characterized by factor VIII (FVIII) deficiency, can be managed with factor replacement therapy. However, FVIII-neutralizing antibodies developed in people with hemophilia A (PwH) can reduce treatment efficacy. This study investigated t…
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