ASAIO journal (American Society for Artificial Internal Organs : 1992)
Effect of Pulse Frequency on Shear-Induced Extension of Von Willebrand Factor in Continuous-Flow Ventricular Assist Device (CF-VAD).
Esraa Ismail, Javier E Dominguez De Leon, Jay P Sah, Ian C Berg, Guruprasad Giridharan, Palaniappan Sethu, Xuanhong Cheng
Published: 202510.1097/MAT.0000000000002630
Abstract
Patients with continuous-flow ventricular assist devices (CF-VADs) face an elevated risk of nonsurgical bleeding. One hypothetical cause is that the loss of pulsatility promotes unraveling and enzymatic degradation of von Willebrand factor (VWF), a k…
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