International journal of surgery (London, England)
Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression.
Yiying Tao, Xibing Ding, Wei Xuan, Hao Zhu, Xiaohua Liu, Yuqing Chen, Jialin Wu, Jing Du, Jie Tian, Guojun Qian
Published: 202610.1097/JS9.0000000000004592
Abstract
PURPOSE: Aging and metabolic syndrome (MetS) are intertwined risk factors for breast cancer (BC), but the core molecular nexus integrating these states is unknown. This study aimed to identify and validate a causal driver at this intersection. METHOD…
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