International journal of surgery (London, England)
Exploring the role of GLS1 in colorectal cancer progression through the glutamine metabolism-PI3K signaling-autophagy axis.
Yang Xie, Lu Han, Yiyi Jin, Jun Li, Qing Tao, Yonghui Wu, Zide Liu, Chaotao Tang, Xingxing He, Youxiang Chen, Chunyan Zeng
Published: 202510.1097/JS9.0000000000004406
Abstract
BACKGROUND: Glutamine and glutamate metabolism play crucial roles in the development of various tumors, yet their specific involvement in colorectal cancer (CRC) remains poorly understood. PURPOSE: This study aimed investigate the roles of glutamine…
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