International journal of surgery (London, England)
Disrupting of tissue-resident FOLR2+tumour-associated macrophages-derived interleukin-10 improves anti-PD-1 efficacy in gastric cancer.
Anwei Xue, Yifan Cao, Kuan Yu, Tianwei Xu, Ruochen Li, Hongyong He, Chao Lin
Published: 202510.1097/JS9.0000000000004105
Abstract
BACKGROUND: Our previous studies have demonstrated monocyte-derived tumour-associated macrophages (TAMs) secret CXCL8, which induces autonomous PD-L1 expression resulting in immune suppressive microenvironment. However, the role of tissue-resident ma…
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