Unveiling metabolic pathway dysregulation in the malignant transformation of polyps to colorectal cancer: a single-cell analysis of epithelial cell trajectories.

BACKGROUND: Although metabolic reprogramming in colorectal cancer (CRC) has been studied, the changes in metabolic pathways and cellular communication from a healthy colon to precancerous adenoma and CRC remain poorly understood. MATERIALS AND METHOD…

Preview only. Read the full abstract at the source